NEW AMIDES OF SULPHONAMIDES: SYNTHESIS AND BIOLOGICAL EVALUATION
نویسندگان
چکیده
منابع مشابه
Aromatic benzotriazole amides--synthesis and biological evaluation.
Four derivatives of benzotriazole-5-carboxylic acid were synthesized as potential UV-light dependent DNA cleaving agent. The effect of these compounds on phiX174 RF1 phage DNA and pBR322 plasmid DNA was investigated with and without UV exposure. It has been found that the two compounds exert the influence on topological forms of DNA.
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در این تحقیق روشی جهت سنتز یک سری از کمپلکس های پلاتین (ii) حاوی لیگاند های دهنده ی فسفری شامل فسفیت و فسفین ارائه شده است. واکنش پیش ماده ی پلاتین (ii)،trans/cis- [ptcl2(sme2)2] ، با 2 اکی مولار از لیگاند p(oph)3در حلال بنزن کمپلکس1، cis-[ptcl2(p(oph)3)2] را تولید می نماید. جهت سنتز کمپلکس سایکلو متال فسفیتی، کمپلکس 1 با 1 اکی والان واکنشگر ptcl2 در حلال زایلن در شرایط رفلاکس زیر گاز آرگون م...
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As a continuous research for discovery of new COX-2 inhibitors, chemical synthesis, in vitro biological activity and molecular docking study of anew group of 1,4-dihydropyridine (DHP) derivatives were presented. Novel synthesized compounds possessing a COX-2 SO2Me pharmacophore at the para position of C-4 phenyl ring, different hydrophobic groups (R1) at C-2 position and alkoxycarbonyl groups (...
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ژورنال
عنوان ژورنال: Journal of the Chilean Chemical Society
سال: 2010
ISSN: 0717-9707
DOI: 10.4067/s0717-97072010000100017